Targeting translation
نویسندگان
چکیده
منابع مشابه
Targeting Translation Dependence in Cancer
A challenge in cancer therapy is to selectively target activities that are essential for survival of malignant cells while sparing normal cells. Translational control represents a potential anti-neoplastic target because it is exerted by major signaling pathways that are often usurped in cancers. Herein we describe approaches being developed that target eukaryotic initiation factor (eIF) 4F, a ...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2012
ISSN: 1740-1526,1740-1534
DOI: 10.1038/nrmicro2870